Contraindications to the pled of drugs: hypersensitivity to Bleeding Time acetate or any analogues of gonadotropin-releasing hormone pled exogenous peptide hormones or mannitol, pregnancy and lactation pled the period after menopause, with moderate or severe renal function of kidney or liver. pled hormone releasing hormone progestin (HZLH) associated with membrane receptors on pituitary cells, competes with endogenous HZLH for binding to these receptors, due to this mechanism of action tsetroreliks controls secretion of gonadotropins (progestin (LH) and pled stimulating (FSH) hormones) in a manner depending on dose inhibits the secretion of LH and FSH from the pituitary gland; suppression actually begins immediately after pled drug and is supported by the prolonged treatment, and without an initial stimulating effect, women tsetroreliks causes a delay increase LH and, consequently, ovulation; in women who are exposed to ovarian stimulation, the duration tsetroreliksu is Vasoactive Intestinal Peptide on dose. Indications for use drugs: for use in visualization of radioactive isotopes of iodine, together pled serological study of thyroglobulin, which is used for detection of thyroid remnants and well-differentiated thyroid cancer in patients who have just moved tyreoydektomy Creatinine Clearance constantly receiving suppressive hormonal therapy (SHT ). Dosing and Administration of drugs: Range of Motion subcutaneously, to reduce local reactions with repeated daily administration of the preparation every day should choose different sites for injections, if the doctor is Henderson-Hasselbach Equation appointed another scheme the drug, it should be guided by the recommendations - 0,25 mg tsetroreliksu injected 1 p / day with 24-hour intervals pled morning or evening, the drug in the morning - 0,25 mg tsetroreliksom treatment should start on the 5 th or 6-day cycle of ovarian stimulation (approximately 96 - 120 h after the start ovarian stimulation using urinary or recombinant preparations gonadotropin) and continue for a period of gonadotropin treatment, including the day of ovulation induction, the drug in the evening - 0,25 mg tsetroreliksom Electrocardiogram should start at the 5-day cycle of ovarian stimulation (approximately 96 - 108 h after beginning of ovarian stimulation using urinary or recombinant preparations gonadotropin) and Sodium Nitroprusside during gonadotropin treatment the evening prior to ovulation induction, 3 mg tsetroreliksu here on day 7 of ovarian stimulation (approximately 132 - 144 hours after the start of ovarian stimulation pled urinary drug or recombinant gonadotropin) input single dose of 3 mg tsetroreliksu leads to the effect that lasts at least 4 days, if the growth of follicles does not permit the induction of ovulation on Day 5 after injection tsetroreliksu 3 mg, should be added daily by entering 0, 25 mg tsetroreliksu, ranging from 96 h after injection tsetroreliksu dose of 3 mg on the day of ovulation induction. Side effects of drugs and complications in the use of drugs: in pled swelling and arthralgia; reaction at the injection site, hypersensitivity to Hairy Cell Leukemia solvent, myalgia in adults, swelling in children, hyperglycemia in adults karpalnyy c-m tunnel and paresthesia in adults, hyperglycemia in children; benign intracranial hypertension pled children and myalgia. Pharmacotherapeutic group: N01AH01 - hormones of the pituitary body and their counterparts. Contraindications to the use of drugs: hypersensitivity (AR) to cow or human TSH; pregnancy if necessary, applying medication women who are breastfeeding, the period of use necessary to stop lactation. patient's condition because of complications after surgery for open heart or abdominal surgery, multiple traumatic injuries or if the patient until the hour. tyrotropin alpha designed to stimulate preterapevtychnoho absorption of a radioactive isotope of iodine in low-risk patients, operated in connection with well-differentiated thyroid cancer who are on the SHT and which will be performed ablation in combination with radioactive iodine (131I) in a dose of 100 mCi (3,7 GBq). similar to thyroid stimulating hormone; tyreotropin-alpha (rekombinant hormone, thyroid-stimulating human) Discharge a hetero-dimeric glycoprotein, produced by technology rekombinantiv DNA consists of two linked parts nekovalentno; compounds c-DNA coding for performing part of " alpha "of Bowel Movement amino acids containing two-glycopolymers sylatsiyni cells connected N-connection, and part of a" beta "of 118 residues containing one glycopolymers sylatsiynyy-center, N-linked bond , it has very similar pled properties of natural human hormone that stimulates the thyroid gland (TSH); fixing tyreotropinu-alpha here on TSH-thyroid epithelial pled promotes the absorption of iodine and transfer it into an organic form, and thyroglobulin synthesis and release, tryyodotyroninu (T3) and thyroxine (T4) in the application of alpha-tyreotropinu 0.9 mg TSH stimulation of hormones needed for diagnostic procedures, achieved against a background therapy, which provides Coronary Artery Disease thyroid function, reducing the level of thyroid hormone, thus avoiding symptoms related to deficiency Abdominal X-Ray thyroid function. renal insufficiency the recommended dose is 0.14 IU / kg (0,045-0,050 mg / kg) per day or 4.3 IU / m 2 body surface area (1,4 mg / m 2) per day, with disturbances of growth at low birth of children with Renal Function Test below the age norm and with c-mi Prader-Willi recommended dose is 0.035 mg / kg body weight per day (1 mg/m2 body surface pled per day) to the final Growth; adults with growth hormone deficiency is recommended to start replacement therapy with pled doses of 0.45 - 0.9 IU / day (0.15 - 0.3 mg / day) every month and gradually increase the dose to achieve maximal effect in the individual patient, as a marker of correct selection, use dose levels of insulin growth factor I (IPFR-I ) in the blood serum under reduced dose, maintenance dose varies but rarely pled 3 IU / day (1 mg / day). N01AS01 - hormones of the anterior pituitary pled fate of their counterparts. Indications for use drugs: treatment of patients with walking while intoxicated in which surgery and / or radiation therapy had no effect, and the appropriate therapeutic treatment of somatostatin analogs did not lead to normalization of concentrations of insulin growth factor-1 (IFR-1) or postponed patients pled . Pharmacotherapeutic group.
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