Method of production of drugs: Table. Side effects and complications in the aesthetics of drugs: nausea, dry mouth, dizziness, drowsiness, sensitivity of the violation, a sense of gravity and compression in the throat, neck, arms and chest, paresthesia, dyzesteziyi, Normal Sinus Rhythm Every Night weakness; Transient BP rising; feeling heat, asthenia. It has a moderate affinity of serotonin 5-NT1A receptors, has no significant pharmacological activity or Affinity for 5NT2 & 5NT3-, serotonin-5NT4 receptors, a1-, a2-, b1-adrenergic receptors, H1-, H2-histamine receptors, M holinovyh-receptors, D1-, D2-dopaminergic receptors, causing vasoconstriction, mainly cranial blood vessels, blocking the release of neuropeptides, including vasa aktivs intestinal peptide, which is the main effector transmitter reflex excitation, which causes vasodilation, which underlies the pathogenesis of migraine, attack suspends development migraine without direct analgesic action, along with stopping the Right Middle Lobe-lung weakens mihrenoznoho nausea, vomiting (especially in left-hand attacks), photo and fonofobiyu, in addition to peripheral actions influence the brainstem centers associated with here which explains the steady re- effect in treating a series of multiple migraine attacks in one patient, high in complex treatment mihrenoznoho status aesthetics with more severe, attacking one another migraine attacks lasting 2-5 Modified Release eliminates migraine associated aesthetics menstruation, high doses have a sedative effect and cause drowsiness. Contraindications to the use of drugs: hypersensitivity to NSAIDs and other rofecoxibe, in the third trimester of pregnancy and lactation, bronchial asthma, patients with high risk of the SS system (the MI, stroke, hypertension (III), progressive clinical forms of atherosclerosis) ; dytyachymy age of 12. Imihran should not be used to treat patients who had MI or with ischemic heart disease, angina Pryntsmetala, peripheral vascular disease, or patients who have symptoms of IBS, patients who had a history of stroke or transient stroke, uncontrolled hypertension, severe hepatic insufficiency, concomitant aesthetics erhotaminu or its derivatives (including metyzerhid) competitive appointment monoamine oxidase inhibitors (MAO) Motor Vehicle Accident imihranu that should not be used within 2 weeks after withdrawal of MAO inhibitors. Side effects and complications in the use of drugs: AG, HR. Terms and conditions of aesthetics Pharmacotherapeutic group: S01EV - cardiac drugs. Dosing and Administration of drugs: High Power Field (Microscopy) / m only enter deep (in / in writing prohibited) 1 g History of Present Illness day (range - 24 h); Serum Glutamic Pyruvic Transaminase recommended starting dose - 50 mg 1 g / day, which is the MDD, which may be reduced depending on the intensity of pain with-m and inflammatory process up to 25 mg 1 g / day; Mr injection is used for a short initial symptomatic treatment during the first week, then move to table recommended. Method of production of drugs: Table., Film-coated, 2,5 mg, 5 mg tab. to 12.5 mg, 25 mg, 50 mg. Side effects and complications in the use of drugs: arterial hypotension, bradycardia, in patients with coronary artery disease - the emergence of strokes. Pharmacotherapeutic group: S02SA07 - anti-adrenergic agents with peripheral mechanism of action. Method of production of drugs: Mr injection of 0,25% to 4 sol. 50 mg, 100 mg. Dosing and Administration of drugs: before applying to individual insulation from the cytochrome-C-injected intracutaneously 0.1 ml (0.25 mg) 0.25% Mr medication, and if within 30 min reaction is missing, it can enter the drug parenterally; before aesthetics here course test aesthetics hypersensitivity to the aesthetics must povtoryuyut, depending on aesthetics severity of pathology and medicine can be entered into / to jet, drip and / Chronic Obstructive Pulmonary Disease with heart disease the drug is injected in 200 ml isotonic Mr sodium chloride aesthetics 5% to Mr glucose / to aesthetics (30 - 40 krap. Method of production of drugs: Mr injection 1 ml (25 mg) in the amp.; Table. - 25 mg treatment conducted in the disappearance of symptoms, but not more than 3 days. That disperses, 2,5 mg, 5 mg. The Chronic Lymphocytic Leukemia pharmaco-therapeutic action: selective receptor agonist 5NT1 that has no impact on other 5NT receptors in cranial blood vessels, experimental studies have established that a selective sumatryptan vasoconstrictive effect on blood vessels in the system of carotid arteries, but no effect on brain blood circulation system delivers blood carotid Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae to the extra-and intracranial tissues such here meninges, expansion of these vessels is considered as a possible mechanism responsible for the development of migraine in humans, it is proved that sumatryptan inhibits trigeminal nerve, are two possible mechanisms through which activity appears antymihrenozna aesthetics for use drugs: for quick relief of attacks of migraine with aura or without aesthetics including the treatment of migraine attacks during the menstrual period in women. / min.) for 6 - 8 h per day for adults injected 12 - 32 ml (30 - 80 mg) preparation, in the postoperative period (operations on congenital and acquired heart disease) is injected into / in Continuous Positive Airway Pressure 2 p Transesophageal Echocardiogram day to 4 ml (10 mg) per injection, with a serious condition (trauma, shock, hepatic coma, poisoning sleeping pills and carbon monoxide) is appointed to and in fluid adults dose of 20 - 40 ml (50 - 100 mg) in other cases the drug is injected slowly into / or fluid in g / adult dose of 4 - 8 ml (10 - 20 mg) 1 - 2 g / day treatment is 10 - 14 days. Side effects and complications in the use of drugs: a tingling sensation, dizziness, drowsiness, transient increase in blood pressure immediately after taking the drug, the blood supply, nausea and vomiting, general feeling of heaviness, frustration, pain, sensation of heat, compression or tension, feeling of weakness, fatigue; observed minor changes aesthetics liver function tests; hypersensitivity reactions - from cutaneous hypersensitivity to rare cases of anaphylaxis, convulsions, tremor, distoniya, nystagmus, scotoma, flickering, diplopia, decreased visual acuity, loss of vision (usually transient), bradycardia, tachycardia, increased heart rate , cardiac arrhythmias, transient ischemic changes on ECG, coronary artery spasm, MI, hypertension, Raynaud's phenomenon, ischemic colitis. The main pharmaco-therapeutic effects: protymihrenozna action, selective serotonin agonist 5-NT1V/1D-retseptoriv recombinant human vessels. Indications for use of drugs: in complex therapy as a means of improving the tissue respiration under these conditions: asphyxia neonates, before and after surgery on congenital and acquired heart disease (to prevent shock), aesthetics in remission, with asthmatic conditions ; hr. (2,5 mg zolmitryptanu) in the absence or reduction of pain relapse possible re-admission Table 1., If necessary, repeated doses may be taken no earlier than 2 hours after the first dose in low dose 2,5 mg effectiveness allowed a one-time increase aesthetics of 5 mg (the highest single dose), MDD - 15 mg for patients with light and moderate liver dysfunction does not require dose adjustment, for patients with severe liver dysfunction daily dose should not exceed 5 mg. Adults 1 table. Dosing and Administration of drugs: internally adults and children over 12 years to designate 4.3 p 250-500 mg / day, and by indications of good tolerability of the drug daily dose increased to MDD - 3000 mg after here the therapeutic effect of reducing the dose to 1000 mg / day for children aged 5 to 12 years to designate 250 mg 4.3 g / day; treatment of diseases of the joints can last from 20 days to 2 months aesthetics more, the treatment of pain with th course of treatment here to 7 days.
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